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Transplantation

Clinical Efficacy of TP10 Complement Inhibitor Demonstrated

Published in Blood Weekly, October 27th, 1997

T Cell Sciences, Inc., Needham, Massachusetts, announced positive preliminary results with respect to efficacy from a Phase I/II clinical trial of the company's complement inhibitor, TP10, in patients undergoing lung transplantation.

A goal of the trial was to determine the ability of TP10 to reduce reperfusion injury and improve lung function in patients with end-stage pulmonary disease who were undergoing lung transplant surgery. Evaluations of the safety of TP10 in this indication continue, and are scheduled to conclude before the end of year.

The results showed that at 24 hours after surgery, significantly fewer of the patients receiving TP10...

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