"Transplantation of Philadelphia Chromosome-Negative Peripheral Blood Progenitor Cells in Patients in Early Chronic Phase CML after Mobilization with ICE-Chemotherapy Followed by Simultaneous Administration of rhIL-

According to an abstract submitted by the authors to the 39th Annual Meeting of the American Society of Hematology, held December 5-9, 1997, in San Diego, California, "Mobilization and transplantation of hematopoietic progenitor cells (HPC) was investigated in patients with chronic phase (CP) CML using polychemotherapy with ICE followed by simultaneous subcutaneous (se) administration of recombinant human (rh) G-CSF and rhIL-3 (group A) or rhG-CSF alone (group B). Twelve patients (2 female, 10 male) in group A with a median age of 41.5 years (range 25-46 years) in early CP CML and 5 patients in group B (all male; median age: 47 years (range 35-56 years)), respectively, were mobilized. ...

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