Transplantation (Conference News)

Artificial Viruses Key To Corneal Transplant Gene Therapy

Published in Blood Weekly, December 15th, 1997

More than 60,000 corneal transplants are performed worldwide annually, restoring sight to people blinded through disease or accident.

But approximately a quarter of these new corneas are destroyed by the recipient's immune system within four years of the operation.

At the British Society for Immunology 5th Annual Congress, held December 2-5, 1997, in Brighton, United Kingdom, Andrew George of Imperial College School of Medicine, London, described attempts to prevent this rejection using human genes and man-made viruses.

Dr. George and his colleagues have shown that tumor necrosis factor (TNF) is important in the process by...

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Source: Blood Weekly (1997-12-15)

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