Published in Blood Weekly, February 2nd, 1998
The use of sensitive and specific methods for rapid, reliable diagnosis of human cytomegalovirus (HCMV) infection is necessary for the timely application of antiviral therapy and for monitoring organ transplant recipients.
The demonstration of viral antigens in peripheral blood leukocytes (PMNLs) and of viral nucleic acids in the same cells or in sera has been supported, indicated Aurelia Gaeta and colleagues, University of Rome, Rome, Italy.
To define the optimum diagnostic protocol when monitoring high-risk patients, Gaeta et al. performed a...
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