Transmission (Parvovirus B19)

Clinical Implications of Reinfection Are Unclear

Published in Blood Weekly, February 2nd, 1998

Intravenous immune globulin may have been the source of parvovirus B19 infection in a young patient.

Although human parvovirus B19 is not found very often in individual blood donations, the potential for B19 contamination of plasma derivatives is high, noted Dean R. Erdman, Centers for Disease Control and Prevention (CDC), Atlanta, Georgia, and colleagues.

B19 is a small, nonenveloped DNA virus with two capsid proteins (VP1 and VP2). Its small size and ability to withstand heat and detergent treatments have hindered efforts to inactivate the virus or to remove it from blood products.

To look for genetic changes in human...

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Source: Blood Weekly (1998-02-02)

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