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Transfusion Medicine

"Allogeneic Peripheral Blood Stem Cell Transplantation in Patients with Early-Phase Hematologic Malignancy: A Retrospective Comparison of Short-Term Outcome with Bone Marrow Transplantation."

Published in Blood Weekly, March 30th, 1998

According to the authors' abstract of an article published in Haematologica, "Background and Objective: Transplantation of mobilized allogeneic peripheral blood stem cells (PBSC) has recently been reported by several groups. However, few patients receiving an allograft in the early stage of their disease have been described so far. Design and Methods: Fifteen patients with early stage hematologic malignancies were transplanted with cryopreserved allogeneic PBSC from HLA-identical siblings. PBSC were collected after priming with 10 (mu)g/kg/day of glycosylated granulocyte colony-stimulating factor (G-CSF, lenograstim). Outcomes were compared to a historical control...

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