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Diagnostics

Single Assay Adequate for Screening Certain HBV Patients

Published in Blood Weekly, August 10th, 1998

A single asparate-aminotransferase assay reading can determine the risk of chronic active hepatitis in patients with positive hepatitis B surface antigen and antibodies to hepatitis B e antigen.

Researcher F. Borg and colleagues found that the addition of hepatitis B virus DNA assays did not improve upon the diagnostic findings of aspartate-aminotransferase.

Hepatitis B surface antigen (HBsAg) and antibodies to hepatitis B e antigen (anti-HBe) coexist, and laboratory tests are often requested to assess histological hepatitis activity. To date, an optimum panel of tests has not been found and the usefulness of HBV DNA assays in this context has not...

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