HSV
Viral Genetic Factors Regulate Number of Genome Copies in Latently Infected Neurons
Published in Blood Weekly, September 7th, 1998
Viral genetic factors that determine in vivo reactivation efficiencies of fully replication competent wild-type HSV strains have not been identified, noted N.M. Sawtell, Children's Hospital Medical Center, Cincinnati, Ohio, and colleagues.
A common laboratory strain, KOS reactivates in vivo at lower efficiencies than either strain 17syn+ or strain McKrae (Strelow et al., J Gen Virol, 1994;75:2475-2480 and others).
"An important first step in understanding the molecular basis for this observation is...
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Source: Blood Weekly (1998-09-07)
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