"Effect of Potentially Interfering Substances in the HIV bDNA Assay."

According to an abstract submitted by the authors to the 38th Interscience Conference on Antimicrobial Agents and Chemotherapy, held September 24-27, 1998, in San Diego, California, "The HIV-bDNA is a non-enzymatic method for measuring HIV-1 viral load in plasma. This assay is based on the recovery by centrifugation of the viral particles, the lysis of these viruses and the subsequent hybridization of HIV-1 RNA to oligonucleotide probes complementary to the most conserved regions of the HIV-1 pol gene. The goal of our study was to evaluate the potential interference of i) diverse biochemical substances, whose levels may be altered in plasma, and ii) different antiretroviral drugs, on the...

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