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Prion-Specific Antibodies May Lead to Blood Test

Published in Blood Weekly, December 14th, 1998

Researchers hope that a test for the detection of prions in animal tissue ultimately can be applied to human blood.

The disease-specific form of the prion protein is believed to be part of the infectious particle that causes bovine spongiform encephalopathy (BSE) in cattle, scrapie in sheep, or Creutzfeldt-Jakob disease (CJD) in humans.

Prionics AG (Zurich, Switzerland) has developed a BSE/scrapie screening test, which is a rapid diagnostic system for the detection of prions. The test system works directly with homogenized central nervous system (CNS) tissue and requires no further purification or concentration steps, Bruno Oesch of Prionics...

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