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Stem Cell Transplantation

"ABO Incompatibility as a Prognostic Factor in Allogeneic Stem Cell Transplantation."

Published in Blood Weekly, December 28th, 1998

According to an abstract submitted by the authors to the 51st Annual Meeting of the American Association of Blood Banks, held October 31 - November 4, 1998, in Philadelphia, Pennsylvania, "Background: Allogeneic stem cell transplantation across ABO barriers may result in a variety of immune-mediated disorders, ranging from hemolysis to RBC aplasia. These complications may either be avoided or respond to supportive care and have not been associated with poor outcomes. We therefore adopted a policy in ABO incompatible transplantation that incorporated minimal manipulation of the recipient and the graft or of transfused blood components after transplantation. Methods: A...

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