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Conference Coverage (Tissue Sealants-Europe)

Dried Polymerized Fibrin Sheets Arrest Bleeding

Published in Blood Weekly, December 28th, 1998

The use of a fibrin sheet may solve many practical problems encountered with the use of two-component (fibrinogen and thrombin) liquid fibrin glue.

It is difficult to apply fibrin glue in the two-component liquid form at certain surgical sites because of overflow, before it solidifies, despite the use of an applicator, noted Lissy K. Krishnan and colleagues, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, India.

The use of currently available fibrin glue products for surgical applications is associated largely with two procedures: 1) reconstitution of the lyophilized components; and 2) precise delivery of the mixed...

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