Bone Marrow Transplantation

Immune Reconstitution with T-Cell-Depleted Marrow

Published in Blood Weekly, February 1st, 1999

Children experienced better immune reconstitution than did adults after undergoing T-cell-depleted unrelated bone marrow transplantation, researchers reported.

Although disease-free survival (DFS) continues to improve after unrelated bone marrow transplantation (BMT), fatal opportunistic infections still frequently occur.

T.N. Small and colleagues of New York's Memorial Sloan-Kettering Cancer Center evaluated features unique to immune reconstitution following unrelated BMT ("Comparison of Immune Reconstitution after Unrelated and Related T-Cell-Depleted Bone Marrow Transplantation: Effect of Patient Age and Donor Leukocyte Infusions," Blood,...

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Source: Blood Weekly (1999-02-01)

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