Hemophilia

HIV Lends Hand To Hemophilia Gene Therapy

Published in Blood Weekly, February 8th, 1999

Researchers said they had found a possible way to use HIV as an effective delivery system for gene therapy.

Their tests in mice show a crippled version of the virus - one in which only a single gene is intact - might be used to deliver new genes that can help cure haemophiliacs.

Writing in the journal Science, Inder Verma and a team of colleagues at the Salk Institute in La Jolla, California, said their highly abbreviated HIV virus successfully "infected" mice with human blood cells.

Better yet, they think they hit some of the stem cells - the so-called nursery cells that give rise to all other cells. In the blood, such...

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Source: Blood Weekly (1999-02-08)

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