Transmissible Spongiform Encephalopathy

Curing of [URE3] May Be Applied to Other Prion Diseases

Published in Blood Weekly, March 8th, 1999

It may be possible to "cure" an infectious protein.

The term "prion" means "infectious protein." This concept arose from studies of the mammalian transmissible spongiform encephalopathies (TSEs) (Alper et al., Nature, 1967:214:764-766; Griffith, Nature, 1967;215:1043-1044).

The [URE3] nonchromosomal genetic element is a prion of Ure2p, a regulator of nitrogen catabolism in the yeast Saccharomyces cerevisiae. Ure2p^1-65 is the prion domain of Ure2p, sufficient to propagate [URE3] in vivo, indicated U.S. National Institutes of Health researcher Herman K. Edskes and colleagues ("The [URE3] Prion Is An Aggregated Form of Ure2p That Can...

Want to see the full article?

Purchase this article for only $3.00

We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.

Welcome to NewsRx!

Learn more about a six-week, no-risk free trial of Blood Weekly

Source: Blood Weekly (1999-03-08)

NewsRx is Social

Top Medical Newsletters

Awards

Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005

Facts & Stats

NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.

Google 2010 PageRank: #2 Among Top Health News and Media Publications
Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry