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Hypertension

Lead Exposure Associated with Hypertension in Women

Published in Blood Weekly, March 15th, 1999

Bone lead may be a risk factor for hypertension in non-occupationally exposed women.

Susan A. Korrick, MD, MPH, of Harvard Medical School, and her associates studied 284 participants of the Nurses Health Study (89 hypertensive cases and 195 qualified controls) ("Lead and Hypertension in a Sample of Middle Aged Women," American Journal of Public Health, March 1999;89:330-335). Subjects' blood pressure was determined initially, as were bone and blood measurements. The mid-tibial shaft and the patella were measured for bone lead via K-X-ray fluorescence.

"Results of these analyses indicate a cross-sectional association between bone lead (specifically,...

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