"Predictive Value of Past and Current Screening Tests for Syphilis in Blood Donors: Changing from a Rapid Plasma Reagin Test to an Automated Specific Treponemal Test for Screening."

According to the authors' abstract of an article published in Transfusion, "Background: This study evaluated the change from a rapid plasma reagin (RPR) test to an automated, specific, treponemal test (PK-TP) in screening for syphilis in blood donors. Study Design And Methods: A cross-sectional seroprevalence analysis was performed on 4,878,215 allogeneic blood donations from 19 American Red Cross Blood Services regions from May 1993 through September 1995. Positive predictive values relative to the confirmatory fluorescent treponemal antibody absorption test (FTA-ABS) were calculated. Differences in seroprevalence were compared in RPR and PK-TP tests for 1)...

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