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Tissue Engineering

Functional Arteries Grown Using Novel System that Simulates Fetal Environment

Published in Blood Weekly, April 26th, 1999

A Duke University Medical Center researcher, using a novel "bioreactor" system that mimics the fetal environment, has used cells taken from adult pigs' arteries to grow blood vessels that look and act like the real thing.

When implanted back into the same animals, the arteries functioned much like native vessels, said Dr. Laura Niklason, who published the results of her team's experiments in the April 16, 1999, issue of the journal Science.

While there are many biological and technical hurdles to be overcome before such an approach could be considered for use in humans, such as to treat heart disease, the researchers said this development...

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