"HCV Infection in Infants and Children."

NIH Grant Number: 1Z01CL02079-03. Principle Investigator: N. Luban. Description: "It has become apparent from multiple studies that hepatitis C virus (HCV) infection is very indolent and that serious sequelae (cirrhosis, carcinoma) occur in less than 10% of persons during their first 20 years of infection. It is presumed that the proportion with severe outcomes will increase as the duration of follow-up increases. A corollary to these findings is that most persons who acquire this infection late in life will not be seriously affected by their HCV infection, whereas those who acquire the infection in childhood and young adulthood may be at increased risk...

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