"Ziracin: A Novel Antibiotic against Bb."

According to an abstract submitted by the author to the 12th International Conference on Lyme Disease and Other Spirochetal and Tick-Borne Disorders, held April 9-10, 1999, in New York, New York, "A novel antibiotic, ziracin, was tested for its ability to inhibit growth, in vitro, of the Lyme disease spirochete B. burgdorferi (Bb) and to cure C3H mice of an acute Bb infection. For the in vitro experiments, the MICs (based on {{>=}}90% growth inhibition) and the MBCs (100% killing) for ziracin were compared with those for penicillin (Pen) and ceftriaxone (Ctx). Selected Bb strains (3 reference strains: B31, 297 and CA287; and 27 recent patient isolates) were cultured in a...

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