Orthopedic Surgery

Strong Fibrinolysis in Surgical Wound After Closure

Published in Blood Weekly, August 30th, 1999

Strong fibrinolysis in drained blood from the surgical wound after orthopedic surgery may, if infused, impair general hemostasis.

C.D. Krohn and colleagues performed a study to evaluate the fibrinogen enzymatic conversion in blood collected postoperatively from a surgical wound ("Fibrinogen, Fibrin and Its Degradation Products in Drained Blood after Major Orthopaedic Surgery," Blood Coagul Fibrinolysis, 1999;10(4):167-71).

Ten otherwise healthy patients (aged 11-28 years) requiring surgical treatment for thoracic scoliosis were included in the study. The researchers compared arterial blood preoperatively and at wound closure with samples of drained...

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Source: Blood Weekly (1999-08-30)

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