Coronary Artery Bypass

Effect of Prophylactic Epsilon-ACA on Transfusion Needs

Published in Blood Weekly, September 13th, 1999

Epsilon-aminocaproid acid after heparinization, but before cardiopulmonary bypass, did not greatly reduce postoperative blood loss in coronary artery bypass patients.

Antifibrinolytic medications administered before skin incision decreased bleeding after cardiac surgery. Numerous case reports indicated thrombus formation with administration of epsilon-aminocaproic acid (epsilon-ACA).

C.A. Troianos and colleagues, The Mercy Hospital of Pittsburgh, Pennsylvania, performed a study to examine the efficacy of epsilon-ACA administered after heparinization, but before cardiopulmonary bypass, in reducing bleeding and transfusion requirements after primary...

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Source: Blood Weekly (1999-09-13)

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