Published in Blood Weekly, September 13th, 1999
Antifibrinolytic medications administered before skin incision decreased bleeding after cardiac surgery. Numerous case reports indicated thrombus formation with administration of epsilon-aminocaproic acid (epsilon-ACA).
C.A. Troianos and colleagues, The Mercy Hospital of Pittsburgh, Pennsylvania, performed a study to examine the efficacy of epsilon-ACA administered after heparinization, but before cardiopulmonary bypass, in reducing bleeding and transfusion requirements after primary...
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