Gene Delivery (Transgenes)

In utero Gene Delivery Successfully Accomplished in Sheep

Published in Blood Weekly, September 13th, 1999

Ultrasound-guided, percutaneous adenovirus vector administration into the umbilical vein successfully delivered transgenes to fetal sheep.

M. Themis, H. Schneider, and colleagues from several colleges in the United Kingdom and from Transgene, Strasbourg, France, investigated in utero somatic gene therapy for the treatment of inherited disorders. Their study results were reported in the journal Gene Therapy ("Successful Expression of (beta)-Galactosidase and Factor IX Transgenes in Fetal and Neonatal Sheep after Ultrasound-Guided Percutaneous Adenovirus Vector Administration into the Umbilical Vein," Gene Therapy, 1999;6(7):1239-48).

"In utero...

Want to see the full article?

Purchase this article for only $3.00

We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.

Welcome to NewsRx!

Learn more about a six-week, no-risk free trial of Blood Weekly

Source: Blood Weekly (1999-09-13)

NewsRx is Social

Top Medical Newsletters

Awards

Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005

Facts & Stats

NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.

Google 2010 PageRank: #2 Among Top Health News and Media Publications
Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry