Heart Disease (Genetic Risk Factors)

Blood Vessel Abnormality Runs in Families

Published in Blood Weekly, October 18th, 1999

Individuals with a family history of premature coronary artery disease - occurring before age 60 - were found to have an impaired ability to regulate blood flow to the heart, increasing their risk of a heart attack, say researchers in the October 5, 1999, issue of Circulation,a journal of the American Heart Association.

The findings lead further support to the role of genes in the development of heart disease.

The impaired blood flow is caused by a problem in the cells lining the inner walls of coronary arteries, called the endothelium. The cells help blood vessels expand and relax. Because of the crucial role played by the endothelium cells, this...

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Source: Blood Weekly (1999-10-18)

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