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Erythroid Progenitors (Technology)

Method Allows Proliferation of Large Numbers of Erythroid Progenitors in Culture

Published in Blood Weekly, November 15th, 1999

A method that allows the proliferation of large numbers of human erythroid progenitors should be useful for studying erythropoietic regulation, according to a report from France.

In humans, studies of the erythroid cell lineage are impeded by difficulties in obtaining sufficient numbers of erythroid progenitors. These progenitors in bone marrow or peripheral blood are scarce, and no specific antibodies are available, noted J.M. Freyssinier and colleagues.

Freyssinier et al. described a new method which allows proliferation in liquid culture of large numbers of pure normal human erythroid progenitors ("Purification, Amplification and Characterization...

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