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Acute Myeloid Leukemia (Prognosis)

Vascular Endothelial Growth Factor Levels Predict Outcome

Published in Blood Weekly, January 20th, 2000

Cellular vascular endothelial growth factor level is an independent predictor of outcome in some patients with acute myeloid leukemia, according to researchers in the United States.

Vascular endothelial growth factor (VEGF) is a potent mitogen for vascular endothelial cells. VEGF has been associated with angiogenesis, growth, dissemination, metastasis, and poor outcome in solid tumors.

A. Aguayo and colleagues performed a study to assess cellular VEGF levels and their prognostic significance in newly diagnosed acute myeloid leukemia (AML) ("Cellular Vascular Endothelial Growth Factor Is a Predictor of Outcome in Patients with Acute Myeloid...

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