Coronary Revascularization

Bivalirudin Is Effective in Patients with Cardiac Disease

Published in Blood Weekly, January 20th, 2000

Bivalirudin is safer than and as effective as heparin in treating patients with ischemic heart disease, according to a report from the United States.

Current treatment strategies for percutaneous coronary revascularization and acute coronary syndromes incorporate thrombin inhibition with either unfractionated or fractionated heparin. The peptide bivalirudin (Hirulog) is a direct thrombin inhibitor whose pharmacological properties differ from those of heparin, noted D.F. Kong and colleagues.

Kong et al. conducted a systematic overview (meta-analysis) to assess the effect of bivalirudin on four end points: death, myocardial infarction, major...

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Source: Blood Weekly (2000-01-20)

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