Stem Cells

HIV Based Gene Transfer Systems Are Effective

Published in Blood Weekly, February 3rd, 2000

Recent findings indicate that HIV-based gene transfer systems offer an effective way for transducing human hematopoietic stem cells.

The efficient transduction of human hematopoietic stem cells (HSC) to the extent that they fully retain their engraftment potential and maintain high levels of transgene expression has not been reached, using current murine-based (MLV) retroviral vectors.

Integration of MLV-based vectors requires cells division by using different combination of cytokines in vitro that may effect the engraftment potential of HSC. Lentiviral vector-based gene delivery does not require cell proliferation; therefore, it may offer a more...

Want to see the full article?

Purchase this article for only $3.00

We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.

Welcome to NewsRx!

Learn more about a six-week, no-risk free trial of Blood Weekly

Source: Blood Weekly (2000-02-03)

NewsRx is Social

Top Medical Newsletters

Awards

Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005

Facts & Stats

NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.

Google 2010 PageRank: #2 Among Top Health News and Media Publications
Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry