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Epstein-Barr Virus

Interleukin-10 May Augment Host Immune Response

Published in Blood Weekly, February 10th, 2000

Researchers from the United Kingdom investigated the way proinflammatory cytokines mediate antibody-dependent cellular cytotoxicity in Epstein-Barr virus (EBV).

It is well known that adaptive immune responses, particularly cytotoxic T lymphocytes (CTLs), play a key role in the long-term control of EBV infection. It is becoming increasingly evident, however, that cells of the innate immune response such as monocyte/macrophages play an important role in the initiation and maintenance of adaptive immune responses to invading pathogens, indicated Shahram Salek-Ardakani and colleagues.

In line with this, it has been demonstrated that EBV can interact...

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