Published in Blood Weekly, February 10th, 2000
Hypercoagulability is a commonly exhibited endotoxemia septic symptoms which can contribute to the manifestation of disseminated intravascular coagulation presenting threats to cardiovascular functions. The underlying mechanism, however, remains largely complex and unknown, noted A. J. Chu and colleagues.
Chu et al. herein determined whether bacterial endotoxin (LPS) upregulates the activities of clotting factors in plasma, contributing to extrinsic hypercoagulation ("Compound 48/80 suppresses monocytic...
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