Published in Blood Weekly, March 9th, 2000
Research has shown that terminal carbohydrates on glycoproteins exist in polymorphic forms, both between and within species. Data have shown that the ABH (or AB0) blood group system in humans determines whether A- or B-specific natural antibodies (NAb) occur in an individual.
"Most mammals express the Gal((alpha)1,3)Gal terminal carbohydrate, but humans and Old World primates do not, having no functional (alpha)1,3galactosyl-transferase ((alpha)1,2GT) gene and in analogy with the AB0...
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