Antibody Neutralization

AB0 Blood Group Antigens on Viruses Serve as Targets for Neutralizing Antibodies

Published in Blood Weekly, March 9th, 2000

AB0 blood group antigens serve as targets for neutralizing natural antibodies against viruses, reported researchers from the United Kingdom and the United States.

Research has shown that terminal carbohydrates on glycoproteins exist in polymorphic forms, both between and within species. Data have shown that the ABH (or AB0) blood group system in humans determines whether A- or B-specific natural antibodies (NAb) occur in an individual.

"Most mammals express the Gal((alpha)1,3)Gal terminal carbohydrate, but humans and Old World primates do not, having no functional (alpha)1,3galactosyl-transferase ((alpha)1,2GT) gene and in analogy with the AB0...

Want to see the full article?

Purchase this article for only $3.00

We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.

Welcome to NewsRx!

Learn more about a six-week, no-risk free trial of Blood Weekly

Source: Blood Weekly (2000-03-09)

NewsRx is Social

Top Medical Newsletters

Awards

Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005

Facts & Stats

NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.

Google 2010 PageRank: #2 Among Top Health News and Media Publications
Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry