Reperfusion

Controlled Reperfusion with Modified Solution Reduces Injury

Published in Blood Weekly, March 23rd, 2000

Controlled reperfusion with a modified solution limits pulmonary injury following ischemia, according to researchers in the United States.

A.O. Halldorsson and colleagues reported that in their initial studies they infused this modified reperfusate at a pressure of 40 to 50 mm Hg to insure distribution. "However, perhaps a lower pressure, which is closer to the normal physiologic pressure in the lung, would improve results by decreasing sheer stress," Halldorsson et al. wrote ("Lowering reperfusion pressure reduces the injury after pulmonary ischemia," Annals of Thoracic Surgery, 2000;69(1):198-203).

Fifteen adult pigs underwent two hours of...

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Source: Blood Weekly (2000-03-23)

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