Hematopoietic Growth Factors

Megakaryocyte Late Progenitor Cells Are Expanded

Published in Blood Weekly, March 23rd, 2000

Using hematopoietic growth factors, researchers in France expanded ex vivo megakaryocyte late progenitor cells for use as complementary transplant products in neuroblastoma patients undergoing transplantation with CD34⁺ cells.

P. Halle and colleagues reported that in their experience, patients with neuroblastoma who undergo transplantation with CD34⁺ cells following high-dose chemotherapy have prolonged delays in platelet recovery. In vitro expansion of megakaryocyte (MK) cells may provide a complementary transplant product able to enhance platelet production in the recipient.

Halle et al. performed a study to investigate the...

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Source: Blood Weekly (2000-03-23)

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