Published in Blood Weekly, April 13th, 2000
The Sardinian population is known to have a high prevalence of genetic hemoglobin disorders. Previous studies have reported that an estimated 13% to 33% of Sardinians carry a mutant allele of the alpha-globin gene (alpha-thalassemia trait) and that 6% to 17% of the individuals who have this mutant are beta-thalassemia carriers. "In this population, a single mutation of beta-globin gene (Q39X, beta(0) 39) is...
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