Published in Blood Weekly, June 8th, 2000
"We asked whether 1) multi-fold expanded striatal stem cells can give rise to mature neuronal phenotypes, 2) whether neuronal differentiation can be modulated by extrinsic factors, 3) whether stem-cell derived neurons are functional in vitro and upon transplantation into a rat model of Huntington's disease," reported Viviane Tabar, MD, and colleagues.
Using cells from the rat E14 LGE, researchers caused a 1,500-fold increase in cell number through proliferation in serum-free medium and bFGF. A majority of...
Want to see the full article?
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Blood Weekly
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.