Hematopoietic Stem Cell Grafts

Negative Immunomagnetic Purging Reduces Breast Cancer Tumor Cell Contamination

Published in Blood Weekly, August 17th, 2000

Researchers in Italy found that negative immunomagnetic purging of peripheral blood stem cell harvests from breast cancer patients reduced tumor cell contamination without affecting hematopoietic recovery in these patients.

"Because tumor contamination of hematopoietic stem cell grafts may influence the outcome in breast carcinoma (BC) patients undergoing high-dose chemotherapy (HDC), several ex vivo procedures for the purging of autologous harvests have been investigated," wrote P. Pedrazzoli and colleagues, Osped Niguarda Ca Granda, Italy ("Negative immunomagnetic purging of peripheral blood stem cell harvests from breast carcinoma patients reduces tumor cell...

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Source: Blood Weekly (2000-08-17)

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