Bovine Spongiform Encephalopathy

BSE Transmitted Through Blood Transfusions in Sheep

Published in Blood Weekly, September 28th, 2000

In the September 16, 2000, issue of The Lancet, scientists in the U.K. report preliminary data from an ongoing experiment that suggest that bovine spongiform encephalopathy (BSE), which is caused by the same agent as variant Creutzfeldt-Jakob disease (vCJD), can be passed on by blood transfusions before symptoms in the donor are apparent.

In the study, F. Houston and colleagues at the Institute for Animal Health, Edinburgh, Scotland, fed a breed of U.K. sheep a sample of BSE-affected cattle brain. Sheep were used as the experimental model because they harbor the infectious agent of BSE in tissues other than the brain and spinal cord, as do humans. Blood was...

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Source: Blood Weekly (2000-09-28)

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