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Transplant Tolerance

Researchers Strive to Eliminate Immunosuppressive Drugs in Patients

Published in Blood Weekly, November 9th, 2000

If a transplanted heart was 100% compatible with the patient receiving it, the patient would be cured - not just treated for symptoms of heart disease, said the director of the Pediatric Heart Transplant Program run jointly by All Children's Hospital and the University of South Florida (USF).

"This is the goal we are striving to attain in organ transplantation - total tolerance: the state in which the donor heart is recognized no differently than a fingernail or a toenail or any other part of the body," said Dr. Robert Boucek Jr. "We're not there yet."

More than 80% of children who undergo heart transplants survive many years taking medications...

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