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Gene Transfer

Procedure in Preterm CD34+ Umbilical Cord Blood is Highly Efficient

Published in Blood Weekly, November 23rd, 2000

Gene transfer into CD34+ umbilical cord blood cells from preterm infants is highly efficient, researchers in the United States report.

"Retrovirus-mediated gene transfer has been shown to transduce CD34+ cells from term gestation umbilical cord blood with relatively high efficiency," wrote L.E. Shields and colleagues, University of Washington. "The purpose of this study was to compare the efficiencies of retrovirus-mediated gene transfer into early (23-28 weeks' gestation) and term (37-41 weeks' gestation) umbilical cord blood CD34+ hematopoietic progenitor cells."

Shields et al. published their study in the...

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