Malaria

Blocking Enzyme Imprisons Parasites in Red Cells

Published in Blood Weekly, December 28th, 2000

Researchers have found a way to prevent infectious malaria particles from bursting out of their protective sacs by blocking the activity of a protease, a protein-snipping enzyme.

The research suggests that it might be possible to treat malaria infection with protease inhibitors to keep the infectious particles imprisoned until they deteriorate.

In an article published in the December 12, 2000, issue of the Proceedings of the National Academy of Sciences, Howard Hughes Medical Institute investigator Daniel E. Goldberg and colleagues at Washington University School of Medicine, St. Louis, Missouri, reported that their experiments illuminate a...

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Source: Blood Weekly (2000-12-28)

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