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Blood Transfusion

High-Dose Epoetin Alfa Regimen Optimally Reduces Need Following Total Hip Arthroplasty

Published in Blood Weekly, February 1st, 2001

A high-dose regimen of the hamster-derived glycoprotein epoetin alfa is the best way to prevent the need for allogeneic blood transfusion during hip joint repair surgery, researchers in Canada say.

"The optimum regimen of epoetin alfa for prevention of allogeneic blood transfusion is unknown," according to B.G. Feagan and colleagues at the John P. Robarts Research Institute in Ontario, Canada. So, they conducted a study in patients undergoing hip arthroplasty to pursue this question.

Writing in the Annals of Internal Medicine, the researchers described the results of their randomized, double-blind study, which compared the prophylactic...

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