Published in Blood Weekly, February 8th, 2001
"Dissolution of the fibrin blood clot is regulated in large part by plasminogen activator inhibitor-1 (PAI-1)," explained D.T. Eitzman and colleagues at the University of Michigan. "Elevated levels of plasma PAI-1 may be an important risk factor for atherosclerotic vascular disease and are associated with premature myocardial infarction."
The researchers investigated the role of PAI-1 in curtailing the creation of blood vessel-blocking thromboses after injury to atherosclerotic plaque ("Plasminogen activator...
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