Hematology

Researchers Produce Cell with Universal Myeloid Differentiation Capacity

Published in Blood Weekly, February 22nd, 2001

by Michael Greer, staff medical writer -- Hematologists in the United States have developed a human blood cell line with a surprisingly mercurial nature: it is able to differentiate into granulocytes and macrophages in proportions similar to those found in healthy peripheral blood and bone marrow.

M.A. Baumann and colleagues at the Veterans Administration Medical Center in Ohio described the characteristics of "a human leukemic cell line that appears capable of spontaneous differentiation to all myeloid lineages" in the journal Experimental Hematology.

This cell line, derived from a patient suffering from an aggressive nonchronic myelogenous...

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Source: Blood Weekly (2001-02-22)

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