Published in Blood Weekly, March 22nd, 2001
M. Mohr and colleagues at Germany's University of Munster evaluated the efficacy of performing two procedures for purging malignant B cells from leukapheresis products. They aimed antibody-enriched immunobeads at B cells during immunomagnetic selection of CD34+ stem cells to enable the "simultaneous capture of residual B cells within a closed system."
Simultaneous double purging produced a product with up to 4.5 log steps fewer B...
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