Cardiac Surgery

Complete Blood Replacement Best During Hypothermic Circulatory Arrest

Published in Blood Weekly, March 29th, 2001

by Michael Greer, staff medical writer - Complete blood replacement can prevent adverse neurologic effects during surgical circulatory arrest at extremely low temperatures, anesthesiologists in New York say.

"Profound hypothermia (< 5(degree)C) may afford better neurological protection after circulatory arrest," explained P. Sekaran and colleagues at Columbia University, "however, there are theoretical concerns related to microcirculatory sludging of blood components at these ultra-low temperatures."

Sekaran et al. found that these concerns were well founded. In their study, animals that underwent complete blood replacement had significantly...

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Source: Blood Weekly (2001-03-29)

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