Published in Blood Weekly, April 5th, 2001
"Mice transplanted with bone marrow cells expressing NUP98-HOXA49 through retroviral transduction acquire a myeloproliferative disease (MPD) and eventually succumb to acute myeloid leukemia (AML)," reported E. Kroon et al. ("NUP98-HOXA9 expression in hemopoietic stem cells induces chronic and acute myeloid leukemias in mice," EMBO Journal, 2001;20(3):350-361.)
Bone marrow cells expressing HOXA49 (a gene found at a breakpoint for chromosomal translocations...
Want to see the full article?
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Blood Weekly
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.