Sickle Cell Disease

Bone Marrow Transplant May Reverse Artery Damage In The Brain

Published in Blood Weekly, April 26th, 2001

Cranial artery damage in patients with sickle cell disease may be reversed through bone marrow transplant, according to a recent study in the Annals of Neurology.

St. Jude Children's Research Hospital scientist Grant Steen, PhD, is the author of the study.

Many sickle cell patients suffer from vasculopathy, or damaged blood vessels. The damage may be caused by the high rate of blood flow that is typical of patients with this type of anemia. Because the blood cannot carry as much oxygen, the blood must flow more quickly to bring enough oxygen to the brain.

Pain crises are a well-known symptom of sickle cell disease,...

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Source: Blood Weekly (2001-04-26)

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