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Ischemia

Bone Marrow Implants Increase Neovascularization, Exercise Capacity

Published in Blood Weekly, June 14th, 2001

by Sonia Nichols, senior medical writer - Scientists have found they can induce new vessel growth, restore blood flow, and increase exercise capacity in rodents with blocked arteries by using bone marrow cell implants.

Peripheral arterial blockage, or ischemia, affects exercise capacity by reducing blood flow to the limbs. Bone marrow produces blood cells and other substances in the body that influence new blood vessel growth. S. Ikenaga and colleagues at Yamaguchi University School of Medicine in Japan have discovered that bone marrow cells implanted in rats will cause new blood vessels to form, restoring blood flow to tissues affected by arterial blockage.

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