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Blood Safety

Nucleic Acid Extraction Automation Improves Speed, Cost

Published in Blood Weekly, June 21st, 2001

by Michael Greer, senior medical writer - Full automation of nucleic acid extraction from blood samples is now possible with little or no loss in subsequent testing accuracy.

"Automation of NAT [nucleic acid amplification testing] for single units of blood is currently hampered by the labor-intensive steps involved in the extraction of nucleic acids from samples before the amplification procedures," explained D.H. Lee and colleagues at the New York Blood Center. "A new method has been developed for the automation of these steps using hydrophilic polyvinylidene fluoride (PVDF) filter plates."

Polymerase chain reaction (PCR) testing using nucleic acid...

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