Published in Blood Weekly, June 28th, 2001
"Tissue factor (TF) is known to be present in a high concentration in amniotic fluid," explained M. Uszynski and colleagues at Ludwik Rydygier Medical University. TF promotes blood clotting, and its activity is normally offset by that of tissue factor pathway inhibitor (TFPI).
However, Uszynski and coworkers found that amniotic TFPI may not be able to prevent the procoagulatory effects of TF when amniotic fluid finds its way into the maternal bloodstream.
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